LINS1
  • 30
    Haplo
    Score
  • 0
    Triplo
    Score

Gene Facts External Data Attribution

HGNC Symbol
LINS1 (HGNC:30922) HGNC Entrez Ensembl OMIM GeneReviews LOVD LSDB ClinVar
HGNC Name
lines homolog 1
Gene type
protein-coding gene
Locus type
gene with protein product
Previous symbols
LINS, MRT27
Alias symbols
WINS1
%HI
71.81(Read more about the DECIPHER Haploinsufficiency Index)
pLI
0(Read more about gnomAD pLI score)
LOEUF
0.87(Read more about gnomAD LOEUF score)
Cytoband
15q26.3
Genomic Coordinates
GRCh37/hg19: chr15:101107129-101142389 NCBI Ensembl UCSC
GRCh38/hg38: chr15:100566924-100602184 NCBI Ensembl UCSC
MANE Select Transcript
NM_001040616.3 ENST00000314742.13 (Read more about MANE Select)

Dosage Sensitivity Summary (Gene)

Dosage ID:
ISCA-4606
ClinGen Curation ID:
CCID:007404
Curation Status:
Complete
Issue Type:
Dosage Curation - Gene
Haploinsufficiency:
Gene Associated with Autosomal Recessive Phenotype (30)
Read full report...
Triplosensitivity:
No Evidence for Triplosensitivity (0)
Read full report...
Last Evaluated:
08/22/2016

Haploinsufficiency (HI) Score Details

HI Score:
30
HI Evidence Strength:
Gene Associated with Autosomal Recessive Phenotype (Disclaimer)
HI Disease:
  • intellectual disability, autosomal recessive 27 Monarch

Triplosensitivity (TS) Score Details

TS Score:
0
TS Evidence Strength:
No Evidence for Triplosensitivity (Disclaimer)

Genomic View

Select assembly: (NC_000015.9) (NC_000015.10)