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OXER1 |
Gene Facts External Data Attribution
- HGNC Symbol
- OXER1 (HGNC:24884) HGNC Entrez Ensembl OMIM UCSC Uniprot GeneReviews LOVD LSDB ClinVar
- HGNC Name
- oxoeicosanoid receptor 1
- Gene type
- protein-coding gene
- Locus type
- gene with protein product
- Previous symbols
- No previous names found
- Alias symbols
- GPCR, TG1019, GPR170
- %HI
- 89.85(Read more about the DECIPHER Haploinsufficiency Index)
- pLI
- 0.14(Read more about gnomAD pLI score)
- LOEUF
- 1.91(Read more about gnomAD LOEUF score)
- Cytoband
- 2p21
- Genomic Coordinates
-
GRCh37/hg19: chr2:42989639-42991401 NCBI Ensembl UCSC GRCh38/hg38: chr2:42762499-42764135 NCBI Ensembl UCSC - MANE Select Transcript
- NM_148962.5 ENST00000378661.4 (Read more about MANE Select)
- Function
- Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)- hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins. {ECO:0000269|PubMed:12065583, ECO:0000269|PubMed:12606753}. (Source: Uniprot)
Dosage Sensitivity Summary (Gene)
Dosage ID:
ISCA-23337
Curation Status:
Awaiting Review
Issue Type:
Dosage Curation -
Gene
Haploinsufficiency:
Awaiting Review
Triplosensitivity:
Awaiting Review
Last Evaluated:
Awaiting Review
Haploinsufficiency (HI) Score Details
Review not yet complete.
Triplosensitivity (TS) Score Details
Review not yet complete.
Genomic View
Select assembly:
(NC_000002.11)
(NC_000002.12)
