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There have been deletions reported that include the BCR gene along with other genes (Mikhail et al., 2007; Madan et al., 2010). However, no deletions or mutations of only this gene have been reported at this time. A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. Chronic myelogenous leukemia is not an appropriate phenotype for our purposes.